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The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...
Over the past decade, several novel immunotherapies have transformed the treatment landscape of relapsed or refractory B-cell acute lymphoblastic leukaemia. In the pivotal TOWER trial, blinatumomab—a ...
DESTIN, Fla. — An increasing array of B-cell targeting approaches may aid clinicians in managing the cycles and flares of lupus, according to a speaker at the Congress of Clinical Rheumatology ...
Boehringer Ingelheim has joined the surge of companies entering the B-cell depletion space. But while its peers have largely focused on CAR-Ts and bispecifics, the German drugmaker has paid Cue ...
If your doctor tells you that you have B-cell lymphoma, it means you have a cancer that forms in white blood cells called lymphocytes. Find out what causes it, the symptoms, and the reasons you ...
New study demonstrates how high-affinity B cells 'bank' their best traits instead of rolling the dice and risking deleterious mutations, with implications for better vaccine design.
Explore diffuse large B-cell lymphoma — symptoms, causes, diagnosis, treatment options, and prevention. Learn about its types, risk factors, and prognosis.
For example, results from the phase 3 GOYA study of patients with aggressive B-cell lymphoma showed that an end-of-therapy PET scan showed a 74% reduced risk of death (HR, 0.26; 95% CI, 0.19-0.38 ...
WebMD explains the causes, symptoms, and treatment of B-cell acute lymphoblastic leukemia, a cancer that affects your "B lymphocytes" -- white blood cells that grow in the soft center of ...
SAVANNAH, Georgia — Inebilizumab, a first-in-class anti-CD19 B-cell depleting agent, demonstrated both safety and superior efficacy compared with placebo in patients with seropositive ...
In a new study, researchers examined the efficacy and impact of CD19 CAR T cell therapy on B cells, specifically exploring its ability to deplete B cells in deep tissues and understand the therapeutic ...
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