Cellistic, a pioneer in iPSC-based off-the-shelf cell therapy development and manufacturing services, announces the launch of ...

Cellistic, a pioneer in iPSC-based off-the-shelf cell therapy development and manufacturing services, announces the launch of its Allo Chassistm?ready-to-use, immune-cloaked iPSC cell lines derived ...

Cellistic, a pioneer in iPSC-based off-the-shelf cell therapy development and manufacturing services, announces the launch of its Allo Chassis-ready-to-use, immune-cloaked iPSC cell lines derived from ...

Secretion of soluble factors: MSCs release bioactive molecules like IDO1, TGF-β1, and miR-139 that directly impact CD4 + T cell proliferation and differentiation. Direct cell-cell contact: MSCs ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

Interleukins are cytokines produced and secreted mainly by CD3+ and CD4+ T lymphocytes. Interleukins promote development and differentiation of natural killer cells, T and B lymphocytes and ...

Pharmacologic or genetic inhibition of PGAM inhibited Treg differentiation and shifted CD4 T cells toward a pro-inflammatory, Th17-like state. Mechanistically, we found that PGAM regulates Treg ...

The profiles turned out to be an accurate depiction of the developmental lineage and differentiation ... a quick and accurate way to count CD4 + and CD8 + T cells in HIV-infected patients.

Helper CD4 T cells (Th) represent a diverse collection of subsets with specific cytokines and chemokine profiles that result in activation and growth of cytotoxic T cells, promotion of myeloid cell ...

but also direct action of IL-1 on both CD4 + and CD8 + T cells, either alone or in synergy with prototypical polarizing cytokines, influences T cell differentiation under different conditions. The ...

Clin Immunol, 2011, 141(2): 197-204. [3] Long D, Yang B, Yang M, et al. Bach2 in CD4(+) T cells from SLE patients modulates B-cell differentiation and IgG production [J]. Eur J Immunol, 2023, 53(4): ...