Objective To compare cognitive function between patients with different phenotypes of neuropsychiatric systemic lupus erythematosus (NPSLE) and assess its association with brain and white matter ...

Many people with lupus experience problems with their heart, lungs, and blood . Lupus increases your risk of cardiovascular disease or “heart disease”, which is a leading cause of death among patients ...

Background Abnormalities of type I interferon signaling and production can initiate lupus development. Disturbances of nucleic acid-sensing molecules triggered autoreactivity in lupus mouse models.

Ehrlichia canis (Jaboticabal strain) induces the expression of TNF-α in leukocytes and splenocytes of experimentally infected dogs Amostra Ehrlichia canis (Jaboticabal) induz a expressão de TNF-α em ...

Investigators identified factors associated with sustained complete renal response in lupus nephritis. Achieving sustained complete renal response is feasible in patients with lupus nephritis.

The Michael Jon Barlin Pediatric Lupus Research program provides funding for research projects that have the potential to significantly advance the field of or impact the lives of children living with ...

The FDA has approved Benlysta for SC administration using an autoinjector in patients 5 years of age and older with active LN.

Molecular detection of Ehrlichia canis and Anaplasma platys in dogs in Southern Brazil Detecção molecular de Ehrlichia canis e Anaplasma platys em cães do sul do ...

In the IFNα-accelerated NZB/W lupus model, povetacicept significantly suppressed multiple disease parameters ( figure 1) and reduced key immune cell subsets (including plasma cells) more effectively ...

Through this systematic literature review, we assembled evidence to inform the EULAR recommendations for the non-pharmacological management of systemic lupus erythematosus (SLE) and systemic sclerosis ...

BARCELONA -- A novel antibody-based drug targeting the CD40 ligand helped close to half of patients with treatment-refractory systemic lupus erythematosus (SLE) get symptoms under control ...

Monitoring blood hydroxychloroquine levels could help to ensure that patients with SLE are being treated with the drug optimally, study findings suggest.