Exosomes, the small extracellular vesicles secreted by nearly all cell types, have emerged as powerful players in intercellular communication and potential biomarkers for disease diagnosis and therapy ...

Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradatio ...

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling in cells, a process critical to human health. Their findings, published in ...

RSV infection proceeds by fusion of the viral envelope with the target cell membrane, but it is unclear whether fusion occurs with plasma or endosomal membranes. Entry and/or infection was studied in ...

Researchers at UT Southwestern identified how SNX17 and Retriever interact to regulate endosomal recycling, a crucial process for protein transport. Using cryo-EM imaging, they revealed a key binding ...

ELYSA, endosomal-lysosomal organellar assembly ... Endosomes and lysosomes form giant structures in the periphery of the oocyte plasma membrane MII oocytes were fixed and co-stained with anti-RAB7 and ...

These unique, branched molecules help LNPs break through the endosomal membrane, making them more effective at delivering mRNA and gene-editing tools. In a study in Nature Communications ...

These unique, branched molecules help LNPs break through the endosomal membrane, making them more effective at delivering mRNA and gene-editing tools. In a recent study in Nature Communications ...

Faculty of Life Sciences, Department of Pharmaceutical Sciences, Laboratory of Macromolecular Cancer Therapeutics (MMCT), University of Vienna, Josef-Holaubek-Platz 2, 1090 Vienna, Austria ...