In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

Sickle cell anemia is one of the sickle cell disease ... Hydroxyurea increases the generation of fetal hemoglobin. This can prevent the blood cells from becoming sickle cells.

Right now, approximately 20 billion red blood cells are busy traveling through your blood vessels. They are delivering oxygen ...

An SCD patient in Bahrain received the gene-editing therapy Casgevy, marking the first time the treatment has been given outside the U.S.

This leads to leads to anemia, as well as congestion ... fraction of RBCs still contain a mixture of fetal and adult hemoglobin. Because the sickle-cell mutation is present only on the β-globin ...

Aruvant is developing ARU-1801, a one-time, potentially curative gene therapy for sickle ... functional fetal hemoglobin in β-thalassemia patients and restore normal red blood cell function.

Hydroxyurea Significantly Reduces Infections in Children With Sickle Cell Anemia Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with ...

The quality of life of patients with sickle cell anemia is severely compromised similar to or even worse than patients with other chronic diseases such as arthritis. Patients who responded to ...

The oral small molecules could induce fetal hemoglobin expression. Other companies have hit on the idea of treating sickle cell by inhibiting BACH1. Mitobridge, which Astellas acquired for $225 ...

Hydroxyurea Significantly Reduces Infections in Children With Sickle Cell Anemia Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with ...