In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

Simmie White is taking control of her own story. The six-year-old girl and her mother want others to understand more about ...

An SCD patient in Bahrain received the gene-editing therapy Casgevy, marking the first time the treatment has been given outside the U.S.

Right now, approximately 20 billion red blood cells are busy traveling through your blood vessels. They are delivering oxygen ...

Fulcrum Therapeutics' promising treatment for Sickle Cell Disease and their strong financial position, despite setbacks.

With the addition of Casgevy, Children’s Hospital Los Angeles now offers two gene therapies for sickle cell, the first being Lyfgenia.

“It may indicate an underlying health issue such as low hemoglobin or anemia as it is medically called. One of the reasons of anemia can be Sickle Cell Anemia (SCA)—a genetic blood disorder ...

In children with sickle cell disease ... HbS to <20% and raise hemoglobin to 10-12.5 g/dl (D). If the patient has had a neurological event in the context of severe anemia (e.g. splenic ...

Higher economic deprivation also associated with brain age gap in controls without sickle cell anemia ... intracranial vasculopathy and hemoglobin S percentage were associated with BAG (β ...

Objective This study aims to evaluate the markers of tubular phosphate handling in adults with sickle cell anemia (SCA) and the influence of hydroxyurea (HU), the degree of anemia and Hb F ...

Background Sickle ... anemia is a characteristic of the disease and RBC transfusions are frequently necessary for these patients. There is lack of evidence to recommend specific hemoglobin thresholds ...

If a person inherits only one mutated gene, they are considered a carrier (sickle cell trait) but typically do not exhibit symptoms. Symptoms of sickle cell anemia can vary in severity ... chest ...