Energetic demand and nutrient supply fluctuate as a function of time-of-day, in alignment with sleep-wake and fasting-feeding cycles. These daily rhythms are mirrored by 24-hour oscillations in ...

IN previous experiments 1,2, a rise in serum glucose, and increased endogenous gluconeogenesis in liver slices, was found 5 min after the injection of 50–100 mg of 2-deoxy-glucose (2 DG), an inhibitor ...

Will Kenton is an expert on the economy and investing laws and regulations. He previously held senior editorial roles at Investopedia and Kapitall Wire and holds a MA in Economics from The New School ...

Troy Segal is an editor and writer. She has 20+ years of experience covering personal finance, wealth management, and business news. Ariel Courage is an experienced editor, researcher, and former fact ...

Glycemia refers to the concentration of sugar or glucose in the blood. In the United States and in many other countries, it is expressed as milligrams per deciliter (mg/dl). In many of the European ...

Heterogeneity in the severity of cerebral cavernous malformations (CCMs) disease, including brain bleedings and thrombosis that cause neurological disabilities in patients, suggests that environmental ...

Edited* by Daniel L. Hartl, Harvard University, Cambridge, MA, and approved June 30, 2010 (received for review April 29, 2010) The human gut “metagenome” is a complex consortium of trillions of ...

Objective Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor expressed in tissues with high oxidative activity that plays a central role in metabolism. In this work, we ...

dLiverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK Cerebral malaria is the most severe neurological complication of Plasmodium falciparum malaria. Even though this type of malaria ...

Leigh syndrome is a devastating neurodegenerative disease, typically manifesting in infancy or early childhood. However, also late-onset cases have been reported. Since its first description by Denis ...

Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, ...