Three principal thyroid autoantigens are involved in AITD. These are thyroperoxidase (TPO), thyroglobulin (Tg) and the TSH receptor. Other autoantigens, such as the Sodium Iodide Symporter (NIS ...
Each hormone binds to its cognate receptor in its classical target gland (such as the thyroid for TSH, the gonads for FSH and ...
Receptor or TSH binding inhibition tests (TBII) that do not measure stimulatory activity directly but detect factors in the serum specimen that block the binding of a labeled TSH preparation to an ...
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