Although rheumatologists consider chimeric antigen receptor T-cell therapy “potentially transformative,” nearly 70% remain ...

The Nobel Prize in Medicine was awarded on Monday to three scientists for discovering how a particular kind of cell can stop the body's immune system from attacking itself. The discovery of these ...

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

CAR-T is a powerful tool which is still evolving. Here we highlight what is new in CAR-T cell therapy Cancer cells often play hide-and-seek with the immune system in an attempt to evade catastrophic ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...