Pheiron and Ribo are excited to announce that the first two strategic collaboration milestones have been successfully ...

The first siRNA drug, patisiran, was approved by the U.S ... Potential to make siRNA drugs work better The discovery led the MSK researchers to partner with colleagues from the Icahn School ...

As a molecule, siRNA goes against just about every rule in the traditional drug discovery book. Compared with small molecules, siRNA is large, covered in negative charges, and doesn’t easily cro ...

Prof. Dr. Olivia Merkel, Professor of Drug Delivery, explained: “Nanoencapsulation is a highly efficient way to deliver siRNA to targets across the cellular membrane, protecting it from degradation ...

and to CRISPR and siRNA perturbations, among other examples. These studies are the first steps to validate the use of digital twins in drug discovery, setting the stage for more widespread ...

Novo Nordisk has signed a deal with AI-driven protein design company Gensaic to develop tissue-targeted therapies for cardiometabolic diseases. The collaboration is valued up to $354m, but financial ...

Materials & Methods: The NDS consisted of cationic liposomes (carrier, 100–140 nm), doxorubicin (DOX, anticancer drug), siRNA targeted to MRP1 and BCL2 mRNA (suppressors of pump and nonpump ...