DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

Two newly identified disease-causing genes, known as Bzw2 and Eif5a2, have been implicated in early prostate cancer ...

Panel B describes the refined model of KRAS activation informed by the effects of emerging KRAS inhibitors. According to this model, mutant KRAS is able to hydrolyze guanosine triphosphate (GTP ...

Most of us remember two things from high school biology: that mitochondria are the powerhouses of cells and that we inherit stable sets of chromosomes from our two parents. Both truisms are only ...

Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.

Combined infection with bird flu and human flu could lead to mutations of new viruses that could have dangerous public health consequences, agencies have warned. This is following the news that ...

ANOTHER bird flu outbreak has been confirmed at a farm in England, as experts fear the virus is one mutation from becoming pandemic. The government said all poultry on the infected site ...

The pair had helped identify a still-unnamed disease, which they had tied to a particular gene and to a particular somatic mutation—a genetic change that had not been passed down from a parent ...

Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu 610065, China Targeted Tracer ...

HOXA10-AS is involved in cancer progression through the activation of the PIK/AKT, NF-κB, Wnt/β-catenin, Notch, MAPK, and Hippo signaling pathways. These mechanistic investigations provide new targets ...

A group of such cells, called disease-associated hepatocytes (daHeps), showed NRF2 and AKT activation ... Intriguingly, the mutations observed in MASH-induced HCC are indicative of single-stranded ...

And a study published in the journal Science made waves earlier this month when it suggested that the virus is just one mutation away from being easily transmissible between humans. Under lab ...