Clonal hematopoiesis (CH), the benign clonal expansion of hematopoietic stem cells, is often caused by somatic sequence variations in genes associated with hematologic malignancies. Over the past ...

Engineered BiTE molecule draws T cells to eliminate FAP+ modulated smooth muscle cells, reducing plaque burden across mouse atherosclerosis models.

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer treatment-could be a highly effective tool against atherosclerosis, the condition ...

About half of Americans between 45 and 84 have atherosclerosis without knowing it. Diseases linked to atherosclerosis are the leading cause of death in the United States. The condition develops when ...

ABSTRACT: Background: Peripheral artery disease (PAD) is associated with increased cardiovascular and overall morbidity and mortality in patients with predialysis chronic kidney disease (CKD). In ...

Ischemic stroke, a leading cause of global mortality, is often linked to large‐artery atherosclerosis, including carotid artery atherosclerotic disease and intracranial atherosclerotic disease.

1 Metabolic and Cardiovascular Diseases Laboratory, Division of Human Nutrition, Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada 2 Department of Immunobiology, Centre for ...

ABSTRACT: Introduction: In diabetics, hyperglycemia leads to dyslipidemia and liver damage. Integrative therapy combining traditional medicine with a conventional antidiabetic drug is an innovative ...

Panelists discuss how chronic graft-vs-host disease (cGVHD) results from complex biological mechanisms involving inflammation, loss of peripheral tolerance, and fibrotic pathways affecting multiple ...

Previous studies have established a possible link between hyperhomocysteinemia (HHcy) and dyslipidemia. Circular RNAs (circRNAs) play important regulatory roles in the development of atherosclerosis.