The $185B Cancer Surge: Why the FDA’s Fast-Track Pivot is Scaling a New Immunotherapy Era

USANewsGroup.com News Commentary – The global immuno-oncology market is set to explode from its current $35 billion level to ...
BioSpace

Nurix Therapeutics Presents New Translational Data from First-in-Human Clinical Trial of Oral CBL-B Inhibitor NX-1607 Demonstrating Immune Activation and Tumor Microenvironment ...

Data are being presented at the 2025 Society for Immunotherapy of Cancer (SITC) Annual Meeting SAN FRANCISCO, Nov. 07, 2025 (GLOBE NEWSWIRE) -- Nurix Therapeutics, Inc. (Nasdaq: NRIX), a ...
News Medical

Why zinc may be the missing nutrient in childhood asthma care

Scientists explain how zinc deficiency may fuel childhood asthma and allergies, and why supplements could become a safe, low-cost add-on treatment once clinical trials confirm the benefits. Study: The ...
Frontiers

Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice

1 Laboratory of Immunotherapy and Bone Marrow Transplantation, Hadassah Medical Center, The Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel 2 Department of Molecular Biology, ...
Frontiers

Longitudinal CNS and systemic T-lymphocyte and monocyte activation before and after antiretroviral therapy beginning in primary HIV infection

Background: Trafficking of immune cells to the central nervous system is hypothesized to facilitate HIV entry and immune-induced neuronal injury and is mediated by surface proteins such as chemokine ...
The Lancet

Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice

aAIDS Institute and Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong SAR, People's Republic ...
Medscape

Sjögren Subtypes Have Distinct Pathophysiologic Profiles

Sjögren disease (SjD) presents three distinct phenotypes ― B-cell active with low symptom burden, high systemic activity with high symptom burden, and low systemic activity with high symptom burden; ...
Scientific Research Publishing

Koganti, S., Clark, C., Zhi, J., Li, X., Chen, E.I., Chakrabortty, S., et al. (2015) Cellular STAT3 Functions via PCBP2 to Restrain Epstein-Barr Virus Lytic Activation in B ...

ABSTRACT: Epstein-Barr virus (EBV) infects over 90% of the global population, establishing latent infections in most individuals. Under specific conditions like inflammation and immune suppression, ...
Scientific Research Publishing

Heinzel, S., Marchingo, J.M., Horton, M.B. and Hodgkin, P.D. (2018) The Regulation of Lymphocyte Activation and Proliferation. Current Opinion in Immunology, 51, 32-38.

ABSTRACT: Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five ...