During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body.

Investigators found that denileukin diftitox, which targets the interleukin-2 receptor, achieves objective response rates in 44% of patients with cutaneous T-cell ... of IL-2Rα(CD25)/β(CD122 ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

Mar. 25, 2025 — Exposure to antibiotics during a key developmental window in infancy can stunt growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life ...