Magnetic nanoparticles engineered T cells inside living mice and guided them into solid tumors, achieving over 90% tumor ...

Aging immune cells may be sabotaging the body from within. Researchers found that macrophages produce a protein that locks ...

Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

In individuals who started antiretroviral therapy during acute HIV infection, the proliferative capacity of HIV-specific CD8+ ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

Although rheumatologists consider chimeric antigen receptor T-cell therapy “potentially transformative,” nearly 70% remain ...

A study reveals that impaired fatty acid oxidation in tumor-infiltrating CD8⁺ T cells leads to toxic lipid peroxidation and ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an ...

Researchers found an antibody that seems to play a role in people with better lung cancer prognoses, but turning it into a ...

A new study in Nature Communications reveals how immune cells rapidly shut down their response after activation, preventing ...

Chemotherapy exerts systemic effects that extend beyond direct tumor cell killing, according to a new study led by Tatiana Petrova, professor at the Faculty of Biology and Medicine at the University ...