A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...
Hydrogenases catalyze the reversible splitting and production of hydrogen gas (H2), using complex catalytic cofactors comprising Earth-abundant nickel and/or iron ions. These enzymes, especially the ...
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Scientists uncover how brain enzyme OTULIN controls tau expression
Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the ...
Scientists at the Sloan Kettering Institute have found that increased activity of a normal metabolic enzyme can lead to cancer. The enzyme, SHMT2, is a driver of a large portion of B cell lymphomas ...
Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that ...
PORTLAND, OR – Researchers with the SWOG Cancer Research Network have found that patients with metastatic hormone receptor-positive breast cancer who have low activity levels of the enzyme sTK1 in ...
Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or ...
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