In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...

Right now, approximately 20 billion red blood cells are busy traveling through your blood vessels. They are delivering oxygen ...

Sickle cell anemia is one of the sickle cell disease ... Hydroxyurea increases the generation of fetal hemoglobin. This can prevent the blood cells from becoming sickle cells.

This leads to leads to anemia, as well as congestion ... fraction of RBCs still contain a mixture of fetal and adult hemoglobin. Because the sickle-cell mutation is present only on the β-globin ...

Doctors noticed that patients who had sickle cell anemia, a serious hereditary blood ... the gene that tells the body how to make a form of hemoglobin (Hb), the oxygen-carrying molecule in our ...

Hydroxyurea Significantly Reduces Infections in Children With Sickle Cell Anemia Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with ...

An SCD patient in Bahrain received the gene-editing therapy Casgevy, marking the first time the treatment has been given outside the U.S.

The quality of life of patients with sickle cell anemia is severely compromised similar to or even worse than patients with other chronic diseases such as arthritis. Patients who responded to ...

With the addition of Casgevy, Children’s Hospital Los Angeles now offers two gene therapies for sickle cell, the first being Lyfgenia.