Performing cohesin HiChIP with an optimised fixation method results in a significantly better signal-to-noise ratio, higher ChIP efficiency and improved detection of chromatin loops and stripes ...

RNA sequencing refers to techniques used to determine the sequence of RNA molecules. It includes high-throughput shotgun sequencing of cDNA molecules obtained by reverse transcription from RNA ...

Mar. 24, 2025 — For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new ...