Jan 5, 2025; Glendale, Arizona, USA; Arizona Cardinals wide receiver Marvin Harrison Jr. (18) against the San Francisco 49ers at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images / ...

Despite trades and injuries, the 49ers, with odds at +160, are favored to win the NFC West, sparking debate over their chances against the Rams and Cardinals.