Early CAR T cell expansion is associated with both therapeutic activity and inflammatory toxicity, such as cytokine release syndrome and neurotoxicity. Routine flow cytometry can reliably track ...

When your body’s immune cells attack you instead of protecting you, today’s treatments tamp down the friendly fire but they ...

Scientists are trying a revolutionary new approach to treat rheumatoid arthritis, multiple sclerosis, lupus and ...

A new international multicenter study published in the Journal of Cellular and Molecular Medicine provides important real-world evidence on the use of CD19-targeted chimeric antigen receptor (CAR) ...

The hallmarks of Sjögren's disease are sicca symptoms and dysfunction of the salivary and lacrimal glands, Reed and ...

There's a new frontier in treating autoimmune diseases. Today's treatments tamp down the friendly fire but don't fix what's ...

Researchers identified a key receptor that primes the formation of autoreactive B cells. Disrupting this pathway may be a ...

Barr virus—but new research reveals how it can hijack immune cells, sparking a chronic disease that attacks the body from ...

A peek inside some leading research labs shows how scientists-turned-detectives are painstakingly decoding what causes ...

The treatment landscape for systemic lupus erythematosus (SLE) has shifted greatly in recent years, driven by the emergence ...