Long-term efficacy and safety data on PALSONIFYTM (paltusotine) in acromegaly to be presented, including evidence of both ...

TSH Receptor Autoantibodies (TRAb) The TSH receptor is a member of the superfamily of receptors with seven transmembrane domains linked to G proteins. The 60kb TSH receptor gene located on the ...

Maternal TSH does not cross the placenta, but thyrotropin releasing hormone (TRH) does cross the placental barrier. The physiologic significance of this observation is unknown.

Asif M, Asif A, Rahman UA, et al. Incidence of glaucoma in type 2 diabetes patients treated with GLP-1 receptor agonists: a systematic review and meta-analysis. 2025;8:e70059. doi:10.1002/edm2 ...

The measurement of thyroid hormones in serum is widely regarded as the most valuable single laboratory tool for assessing thyroid function. This study presents a highly sensitive tin disulfide ...

The median, 2.5th and 97.5th of thyrotropin (TSH), free triiodothyronine (FT3), free thyroxine (FT4) and FT3/FT4 ratio were calculated for both genders for every decade from 18 to over 80 years. TSH, ...

A decrease in TSH was associated with a 3-point or more decrease in the Mini-Mental State Examination score over 5 years (OR = 1.45; 95% CI, 1.01-2.09; P = .049).

The human TRH receptor (TRHR) has been cloned and shown to belong to the G protein-coupled seven-transmembrane domain receptor superfamily. Many endocrine disorders arise from mutations of these ...

High-throughput screening of a plant and marine invertebrate extract library to find natural products with rat thyrotropin releasing hormorne (TRH) receptor 2 binding affinity led to the isolation of ...

Background: Vepdegestrant, an oral PROTAC (PROteolysis TArgeting Chimera) ER degrader, showed encouraging clinical activity and was well tolerated in a phase 1/2 study in pretreated patients (pts) ...