Io Biotech Aps has presented preclinical data regarding their Arg1-derived peptide cancer vaccine IO-112 as a potential immunotherapeutic that would allow controlling the tumor microenvironment.

Researchers propose that CNDP2-mediated cooperation can be an effective and specific target for cancer treatment.

Researchers have identified a key role microglia play in melanoma brain metastases progression and mechanisms to target them.

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ...

Researchers studied the gene expression of lymphatic endothelial cells in melanoma (a type of skin cancer) and healthy mouse ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic cancer cells.

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face. Locally advanced tumors in particular can be difficult to treat surgically.

Lung endothelial cells in the tumor microenvironment produced more CXCL12, a compound that attracts plasma cells. In addition, immune T cells, typically in charge of fighting the tumor, were excluded ...

Many cells comprise the tumor microenvironment, but endothelial cells are particularly crucial. They line blood vessels, regulating blood flow and inflammation, and their cell junctions are the ...