The Philadelphia Phillies host the Seattle Mariners in the final matchup of this three-game series at Citizens Bank Park. MLB odds list Philadelphia as a -140 favorite, while the total sits at 8.5. My Mariners vs. Phillies predictions expect a low-scoring affair this afternoon. Read on for my MLB picks for Wednesday, August 20.

When manager Rob Thomson walked to the mound to pull Cristopher Sánchez with one out in the seventh inning, fans began to stand and cheer. The starter handed Thomson the baseball, headed toward the dugout,

Realmuto, who hit his ninth homer, reached base three times and had three RBIs. He also had an RBI single and reached on a catcher’s interference call on Mariners backstop Mitch Garver. It was the third time in a month the Phillies were on the positive side of a catcher’s interference call.

Pregame analysis and predictions of the Seattle Mariners vs. Philadelphia Phillies MLB game to be played on August 20, 2025 on ESPN.