The past decade has seen increasing interest in the tricuspid valve (TV), once referred to as the forgotten valve, as a result of a combination of improved imaging and therapeutic possibilities plus a ...

Aortic valves from EgfrVel/+ mice and control mice were examined by light microscopy at 2.5 to 4 months of age. Additional EgfrVel/+ and control mice underwent echocardiography at 2.5, 4.5, 8, and 12 ...

Abstract —Short-term feeding (up to 7 days) of an atherogenic diet to C57BL/6 low density lipoprotein receptor–deficient mice did not result in decreased hepatic paraoxonase (PON) mRNA but caused a ...

Graphical AbstractIntracranial atherosclerotic stenosis (ICAS) is the most common cause of stroke worldwide and is associated with high risk of recurrence compared with other stroke subtypes. 1–3 ...

Background—We hypothesized that high-sensitivity cardiac troponin (hs-cTn) and its early change are useful in distinguishing acute myocardial infarction (AMI) from acute cardiac noncoronary artery ...

We identify a previously unknown pathway by which cardiac HIF activation promotes the loss of mitochondria and peroxisomes. We found that DEPP1 (decidual protein induced by progesterone 1) is induced ...

Stroke is the second‐leading cause of death globally and ischemic stroke constituted more than 60% of all incident strokes in 2019. 1 Intravenous alteplase thrombolysis was approved by the US Food and ...

Since 1980, the American College of Cardiology (ACC) and American Heart Association (AHA) have translated scientific evidence into clinical practice guidelines (guidelines) with recommendations to ...

As early as 1699, Chemineau described a heart composed of 2 auricles but only 1 ventricle.1 The univentricular heart has since fascinated the medical community. Unique in its complexity and scope, the ...

Valvular repair or replacement is a common final management option in both primary and secondary MR, resulting in ≈50 000 annual mitral valve operations in the United States; however, defining the ...

Aim: This executive summary of the clinical practice guideline for the evaluation and diagnosis of chest pain provides recommendations and algorithms for clinicians to assess and diagnose chest pain ...

Adenoviruses are typically associated with mild respiratory infections, but are increasingly attributed to cardiac infection. Viruses have long been understood to infect the heart, with many studies ...