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3:34
YouTube
Shomu's Biology
Pyruvate dehydrogenase complex mechanism
Pyruvate dehydrogenase complex mechanism http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Pyruvate dehydrogenase (E1) Initially, pyruvate and thiamine pyrophosphate (TPP or vitamin B1) are bound by pyruvate dehydrogenase subunits. The thiazolium ring of TPP is in a ...
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Pyruvate Dehydrogenase Complex Function
Questions:1.) The Pyruvate Dehydrogenase Complex is a haloenzyme. What does that mean?2.) List all the levels of protein structure that PDC would have.3.) What is the reaction catalysed by PDC? List all the products.4.) Vitamin B1 is a cofactor in the PDC (ie. It is necessary for enzyme function) explain why one ofthe symptoms of a vitamin B1 deficiency is fatigue.
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